Yes - you can run a User Overview - Standard Report from Reports > Administration > User Overview - Standard Report.
This will give you a full list of all users, if they are active and what security levels have been selected. We recommend exporting this to Excel to do quick filtering.
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You can also view a screen called 'User List' under Administration > Users > User List.
This will give show you how many manual logins have occurred (will not work with SSO logins however) and if the user is active.
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Reporting within Insights: There is a dataset that you can use to build a report based on this User list. This dataset is called : Planning_UserList_STND